​Liang Fang is an Executive Director and Head of Biostatistics in MyoKardia Inc. His research interests include statistical applications in drug development, 

MyoKardia's lead drug candidate is mavacamten, which it is developing for hypertrophic cardiomyopathy and plans to submit to the FDA in the first quarter of next year.

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MyoKardia is currently preparing a New Drug Application (NDA) for mavacamten, with plans to submit to the FDA in the first quarter of 2021.About HCM Hypertrophic cardiomyopathy (HCM) is a chronic MyoKardia has been trying to show that these drugs can regulate a protein involved with muscle contraction and, in turn, improve heart health. In the case of mavacamten, the company has been testing it in patients with hypertrophic cardiomyopathy, or HCM, a typically inherited condition where the heart muscle gets thicker over time, making it harder to pump blood. Myokardia is expected to submit a marketing application for mavacamten to the U.S. health regulator in the first quarter of 2021. Bristol-Myers said it expects to explore the use of mavacamten for "The lead asset for MyoKardia is mavacamten," which is a "potentially revolutionary medicine for the treatment of the very serious disease of obstructive HCM." MyoKardia Presents Results from Phase 3 EXPLORER-HCM Clinical Trial of Mavacamten for the Treatment of Obstructive Hypertrophic Cardiomyopathy. BRISBANE, Calif., Aug. 29, 2020 (GLOBE NEWSWIRE) -- MyoKardia, Inc. (Nasdaq: MYOK) announced today that 30-week results from its pivotal Phase 3 EXPLORER-HCM clinical trial of mavacamten for the treatment of symptomatic, obstructive hypertrophic cardiomyopathy (HCM) were presented during a live Hot Line session at the European Society of Cardiology MyoKardia is a clinical-stage biopharmaceutical company discovering and developing targeted therapies for the treatment of serious cardiovascular diseases. The company is pioneering a precision medicine approach to its discovery and development efforts by 1) understanding the biomechanical underpinnings of disease; 2) targeting the proteins that modulate a given condition; 3) identifying patient populations with shared disease characteristics; and 4) applying learnings from research and Through the transaction, Bristol Myers Squibb gains mavacamten, a potential first-in-class cardiovascular medicine for the treatment of obstructive hypertrophic cardiomyopathy (“HCM”), a chronic heart disease with high morbidity and patient impact. A New Drug Application (“NDA”) for mavacamten for the treatment of symptomatic obstructive HCM – based on data from the EXPLORER-HCM study – is expected to be submitted to the U.S. Food and Drug Administration (“FDA”) in the first Adobe.

MyoKardia recently announced a new clinical trial of its drug, mavacamten (formerly known as MYK-461) which will compare the clinical results of mavacamten with septal reduction therapies currently used in clinical practice, i.e.

MyoKardia Announces Receipt of Breakthrough Therapy Designation from FDA for Mavacamten for the Treatment of Symptomatic, Obstructive Hypertrophic Cardiomyopathy. BRISBANE, Calif., July 23, 2020 (GLOBE NEWSWIRE) -- MyoKardia, Inc. , (Nasdaq: MYOK) today announced that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation to mavacamten, a novel, oral, allosteric modulator of cardiac myosin, for the treatment of symptomatic, obstructive hypertrophic

A New Drug Application (“NDA”) for mavacamten for the treatment of symptomatic obstructive HCM – based on data from the EXPLORER-HCM study – is expected to be submitted to the U.S. Food and Drug Administration (“FDA”) in the first Adobe. A n experimental drug to treat an inherited, progressive heart disease clearly improved the symptoms of patients, its maker, MyoKardia, said Monday. The full data have not yet been MyoKardia's lead drug candidate is mavacamten, which it is developing for hypertrophic cardiomyopathy and plans to submit to the FDA in the first quarter of next year.

MyoKardia has developed a pipeline of potential therapies to combat cardiovascular diseases, and announced in May that its experimental drug for obstructive hypertrophic cardiomyopathy, mavacamten,

Bristol-Myers is seeking to reduce some of its dependence on cancer Danicamtiv is MyoKardia’s most advanced clinical candidate being developed for the treatment of genetic dilated cardiomyopathy (DCM) and other targeted populations with conditions of reduced systolic function. DCM is a disease of the myocardium characterized by left ventricular enlargement. Bristol Myers Squibb has struck a deal to acquire MyoKardia for $13.1 billion. The all-cash takeover will see Bristol Myers pay a 61% premium to MyoKardia’s closing price on Friday to secure a MyoKardia (NASDAQ: MYOK) is testing its drug, mavacamten, in patients who have obstructive hypertrophic cardiomyopathy (HCM), a hardening and thickening of the heart muscle that makes it harder for It's hard to sell pricey new cardiovascular drugs when most people can get the job done with cheap generics, but this isn't the case with MyoKardia's lead candidate, mavacamten. Its intended MyoKardia has developed a pipeline of potential therapies to combat cardiovascular diseases, and announced in May that its experimental drug for obstructive hypertrophic cardiomyopathy, mavacamten, MyoKardia plans to submit a New Drug Application (NDA) for U.S. regulatory approval in this indication in the first quarter of 2021. Based on mavacamten’s mechanism of action and evidence of therapeutic activity, MyoKardia plans to study mavacamten for the treatment of symptomatic non-obstructive HCM and among a targeted population of patients with heart failure with preserved ejection fraction (HFpEF). MyoKardia is currently preparing a New Drug Application (NDA) for mavacamten, with plans to submit to the FDA in the first quarter of 2021.About HCM Hypertrophic cardiomyopathy (HCM) is a chronic MyoKardia has been trying to show that these drugs can regulate a protein involved with muscle contraction and, in turn, improve heart health.

DCM is a disease of the myocardium characterized by left ventricular enlargement.
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The average salary for Entry Drug Safety/Medical Information Specialist at companies like MYOKARDIA INC in the United States is $83,320 as of January 29, 2021, but the salary range typically falls between $74,800 and $92,510.

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2019-01-02

Drug Development BMS to buy MyoKardia for access to late-stage heart disease drug The $13 billion deal bolsters the big pharma firm’s cardiovascular disease pipeline by Lisa M. Jarvis By Jared S. Hopkins . Bristol-Myers Squibb Co. said it will buy biotech MyoKardia Inc. in a $13.1 billion deal aimed at expanding the cancer-drug powerhouse's lineup of heart drugs. MyoKardia’s Board of Directors unanimously recommends that MyoKardia shareholders tender their shares in the tender offer. The transaction is subject to customary closing conditions, including the tender of a majority of the outstanding shares of MyoKardia’s common stock and the expiration or termination of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of 1976. Learn more about Bristol Myers Squibb and our mission to discover, develop and deliver innovative medicines to patients with serious diseases. Bristol Myers Squibb (NYSE:BMY) announced today that it has successfully completed its acquisition of MyoKardia, Inc. in an all cash transaction for approximately $13.1 billion. With the completion of the acquisition, MyoKardia shares have ceased trading on the NASDAQ Global Select Market and MyoKardia is now a wholly-owned subsidiary of Bristol Myers Squibb.